Desoxy-D2PM: a novel psychoactive substance in convenience stores.
نویسندگان
چکیده
To the Editor—Novel psychoactive substances (NPSs) are recently available unlicensed drugs that are chemically or pharmacologically similar to conventional drugs of abuse. Their rapid and protean emergence has created many challenges for clinicians, laboratories, social workers, and regulatory authorities. Our laboratory has repeatedly identified NPSs.1,2 We report the discovery of 2-(diphenylmethyl)-pyrrolidine (desoxy-D2PM), an NPS present in an over-the-counter slimming product available in local convenience stores. Undeclared desoxy-D2PM was detected in a slimming product branded “B-finn” purchased in Thailand by a patient. Subsequently, we obtained a slimming product of the same brand in a local drugstore and detected the presence of desoxyD2PM. The Department of Health was notified and a product recall was initiated.3 Shortly after, desoxyD2PM was detected in the urine specimen of another unrelated patient. Desoxy-D2PM is structurally related to methamphetamine, which inhibits noradrenaline and dopamine re-uptake. Desoxy-D2PM has been reported to have appetite suppressing, euphoric, and stimulant effects.4 Overdose of desoxy-D2PM may lead to violent behaviour, hallucinations, and sympathomimetic toxicity.4 In Hong Kong, desoxy-D2PM is yet to be listed as a dangerous drug under the Dangerous Drugs Ordinance at the time of writing. Nonetheless its ready availability in drugstores and convenience stores before the recall, and its presence in the urine of an unrelated patient, raise concern about its Hong Kong Med J 2016;22:515 DOI: 10.12809/hkmj166018
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ورودعنوان ژورنال:
- Hong Kong medical journal = Xianggang yi xue za zhi
دوره 22 5 شماره
صفحات -
تاریخ انتشار 2016